Reis was expected to face Hugo Viana at UFC Fight Night 28, but an injury forced Viana out of the fight just days prior to the event and Reis was removed from the card altogether.
On Tuesday, Norifumi “Kid” Yamamoto pulled out of his scheduled UFC 165 bout with Ivan Menjivar and UFC officials announced Reis as Yamamoto’s replacement on the Sept. 21 event.
Reis (16-4) is riding a four-fight winning streak and hopes to continue his winning ways under the UFC banner.
Menjivar (25-10) is coming off a submission loss to Urijah Faber at UFC 157 on Feb. 23 and hopes to rebound by spoiling Reis’ UFC debut.
UFC 165 takes place on Sept. 21 at the Air Canada Centre in Toronto and his headlined by a light heavyweight title bout between champion Jon Jones and challenger Alexander Gustafsson. The co-main event features the interim bantamweight title fight between champion Renan Barao and top contender Eddie Wineland.