FoxSports.com first reported the bout, which was later confirmed by UFC officials.
Kedzie vs. de Randamie will take place on the UFC on Fox 8 fight card slated for July 27 in Seattle.
Kedzie (16-11) is popular among fans, but perhaps more so than many of the other women debuting in the Octagon, needs to make an immediate impression. She lost both of her Strikeforce bouts – to Miesha Tate and Alexis Davis – before making the move with many of the other 135-pound Strikeforce women to the UFC.
A former kickboxing world champion, de Randamie (3-2) went 2-1 during her Strikeforce tenure. The fight with Kedzie marks her return to 135 pounds after fighting at 145 in her last two bouts.
The UFC on Fox 8 event takes place at the KeyArena in Seattle, but has yet to land a main event. UFC flyweight champion Demetrious Johnson, feverishly working to return from injury, has been lobbying for the main event as he currently fights out of neighboring Kirkland, Wash.