The UFC announced the headliner, plus two more bouts, during the UFC Fight Night 59: McGregor vs. Siver telecast on Sunday night on FOX Sports 1.
The co-main event of the Fairfax card features lightweights Bobby Green and Jorge Masvidal, and also includes a bout pitting Michael Chiesa vs. Mitch Clarke.
Mendes (16-2) is currently the No. 1 ranked fighter in the UFC’s 145-pound division. He is coming off of a loss to champion Jose Aldo, the only man to ever defeat him.
Ranked No. 3, Lamas (15-3) is currently 6-1 in the Octagon, having won back-to-back bouts over Hacran Dias and Dennis Bermudez as he heads into the fight with Mendes. Like Mendes, Lamas’ only loss in the UFC is to Aldo.
The UFC Fight Night: Mendes vs. Lamas main card has a special start time of 1 p.m. ET / 10 a.m. PT on FOX Sports 1.