UFC officials announced the bout on Saturday.
Kimura (11-2) has only ever lost after having arrived in the Octagon, where he is 2-2 in his four bouts. He is coming off of a loss to George Roop at the TUF Nations Finale earlier this year in Quebec.
Entwistle (8-2) has fought only once under the UFC banner, losing to Daniel Hooker at the recent UFC Fight Night card in New Zealand.
Kimura and Entwistle are both especially known for their submission abilities, and each needs a victory to secure his spot on the roster.
A five-round middleweight showdown between Ronaldo “Jacare” Souza and Gegard Mousasi headlines UFC Fight Night 50 at Foxwoods Casino in Ledyard, Conn.